Work

Correction: Base-excision repair increases DNA double-strand break clustering within heavy-ion tracks and modulates repair at δ-electron-induced breaks

Year: 2026

Type: erratum

Abstract: “To block the BER pathway, a combination of two inhibitors was used in the cells-culture medium: 10 µM TH5487, an OGG1 inhibitor that prevents OGG1’s binding and repair of 8-oxoG 58,59 and 40 mM methoxyamine (MX), an indirect APE1 inhibitor, as it makes apurinic and apyrimdinic sites insensitive to APE1 60 .”

Source: Scientific Reports

DOI: 10.1038/s41598-026-39156-5

Authors: Laura Schwan, Nicole B. Averbeck, Marco Durante, Burkhard Jakob

Institutions: GSI Helmholtz Centre for Heavy Ion Research, Technische Universität Darmstadt

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,690