Testing Multiple Delivery Methods of the Virtual Exercise Games for Youth with T1D Peer Intervention: Protocol Development and Feasibility
Year: 2026
Type: article
Study design: Clinical Trial
Abstract: INTRODUCTION: Adolescents with type 1 diabetes (T1D) face barriers to moderate-to-vigorous physical activity (MVPA) such as uncertainty with self-management, limited access to supportive environments, and stigma related to living with diabetes. Opportunities for peer activities with T1D role model support are limited. To address this need, we tested iterative refinements of pilot Virtual Exercise Games for Youth with T1D (ExerT1D) for feasibility and acceptability. METHODS: The program included 6 versions: study 1 (1.1-1.4) included an active video game, and study 2 (2.1-2.2) included a virtual reality (VR) active video game. All versions included T1D exercise management education by clinicians and goal-setting guided by young adult coaches with T1D. RESULTS: Seventeen adolescents (median age 15.4 [IQR 14.6-16.4] years, 7 non-Hispanic white, 8 male, median HbA1c 8.1% [IQR 7.4%-11.1%]) were enrolled. Participants rated the program, comfort, clinicians, coaches, and group cohesion high/very high. Motivation for the video game was high. Building T1D and MVPA self-management skills was rated excellent at most sessions, as were peer interactions and enriched communication after adding immersive VR in study 2. Transitions between VR apps caused delays of 19 ± 6 min per 60 min-90 min session. Compared to baseline, HbA1c or glucose management indicator decreased over time in an exploratory analysis (d = -1.12, 90% CI: [-1.78, -0.48]). CONCLUSIONS: In a small cohort, the ExerT1D program facilitated a supportive environment for engaging diverse youth with T1D in an MVPA program led by T1D coaches. Larger studies are needed to assess the intervention's impact on engagement with physical activity, glycemic outcomes, and quality of life.
Source: Hormone Research in Paediatrics
DOI: 10.1159/000550880
Institutions: Yale University, VA Connecticut Healthcare System, Center for the Study of Healthcare Provider Behavior, VA Greater Los Angeles Healthcare System, Yale New Haven Hospital, Columbia University, Southern Connecticut State University, Lurie Children's Hospital, Hong Kong Baptist University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Metabolic and Neurological Changes Induced by a Very Low Carbohydrate Diet in Youth with Type 1 Diabetes, Mobile Approaches to Promote Moderate to Vigorous Physical Activity in Type 1 Diabetes, Informatics-Based Digital Application to Promote Safe Exercise in Middle-Aged Adults with Type 1 Diabetes, Yale Diabetes Research Center
OpenAlex ID: W7129006053
