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Data from: Transcriptomic and methylomic analyses show significant shifts in biosynthetic processes and reduced intrapopulation gene expression variance in PAH-Adapted Atlantic killifish

Year: 2026

Type: dataset

Abstract: Environmental contaminants pose a significant selection pressure across taxa, potentiating evolved resistance to chemicals. However, rapid evolution may alter molecular and physiological homeostasis leading to trade-offs. To elucidate molecular underpinnings of evolved chemical resistance, we compared liver gene expression and methylation profiles in polycyclic aromatic hydrocarbon (PAH)-adapted Atlantic killifish (Fundulus heteroclitus) in the Republic site (RP), Elizabeth River, Virginia with PAH-sensitive Kings Creek (KC) fish. Data herein include alternatively spliced genes, differentially expressed genes, methylation, mRNA read counts, sequenced RRBS, and gene ontologies.

Source: Research Data Repository, Duke University

DOI: 10.7924/r4gx4kv8b

Authors: Di Giulio, Richard T., Harishchandra, Akila, Jayasundara, Nishad

Topic: Environmental Toxicology and Ecotoxicology

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of Environmental Health Sciences

OpenAlex ID: W7129011581

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