Course of well-being and mental health in Switzerland during the COVID-19 pandemic: results of a national survey within the framework of the COH-FIT study
Year: 2026
Type: article
Study design: Observational Study
Abstract: Introduction The COVID-19 pandemic significantly impacted the mental health of the Swiss population. Methods This study analyzed data from the Collaborative Outcome study on Health and Functioning during Infection Times (COH-FIT) across three pandemic waves: T1 (April–June 2020), T2 (July–December 2020) or T3 (January–June 2021). Each participant participated only once, during one of these three waves. Participants reported their subjective well-being and mental health status for the two weeks prior to the pandemic (pre-pandemic baseline) and during their respective pandemic wave. Subjective well-being was assessed using the World Health Organization Well-Being Index (WHO-5) from 4,037 participants, while mental health was measured via the P-score, completed by 3,375 participants. The WHO-5 ranges from 0 to 100, with higher scores indicating better well-being, while the P-score also ranges from 0 to 100 whereas higher scores represent greater levels of perceived burden across five domains of mental health. Pre- and intra-pandemic differences were analyzed using Wilcoxon tests and ANOVA, with subgroup analyses across seven Swiss regions utilizing the Kruskal-Wallis test. Results Participants had a mean age of 45.6 years (61.9% female). Results showed a substantial decline in well-being during the pandemic, with average WHO-5 scores decreasing from 75.3 pre-pandemic, to 66.5 during the first wave, 69.1 during the second, and 65.1 during the third, representing relative reductions of 11.7%, 8.2%, and 13.5%. The percentage of participants at risk for depression (WHO-5 <50) peaked during the third wave at 19.8%, up from 10.0% pre-pandemic. Mental health burden, as measured by the P-score, increased significantly during the first wave (from 20.6 to 27.3, +32.5%), and remained elevated across the two subsequent waves, with no significant recovery observed. Wilcoxon tests indicated significant differences between pre-pandemic and intra-pandemic WHO-5 and P-scores, with the largest effect sizes during the third wave ( r = 0.652 for WHO-5; r = 0.487 for P-score). ANOVA showed significant intra-pandemic differences in WHO-5 across waves ( p < 0.001), with improvements noted in the second wave. However, no intra-pandemic differences in P-scores were found ( p = 0.298). Regional analyses revealed that Ticino, the Lake Geneva region, and Northwestern Switzerland experienced the most pronounced declines in well-being and increases in mental health burden. In contrast, Espace Mittelland and Eastern Switzerland experienced a less severe impact. Discussion Overall, these findings highlight the considerable and lasting impact of COVID-19 on mental health in Switzerland, emphasizing the need for targeted interventions, particularly in the most affected regions.
Source: Frontiers in Psychiatry
Authors: Christian G. Huber, Janina Billian, Tiziana Ziltener, Philippe Conus, Roland von Känel, Gregor Hasler, Jihed Sehli, Anna Mosina, Damir Krinitski, Erich Seifritz, Eva Kowalinski, Isabelle Gothuey, Jennifer Marian, Undine E. Lang, Trevor Thompson, Marco Solmi, Christoph U. Correll, Sabina C. Heuss, Andres R. Schneeberger
Institutions: University of Basel, Universitäre Psychiatrische Kliniken Basel, University of Lausanne, University of Zurich, University Hospital Zurich, University of Fribourg, Clienia AG, Psychiatrische Universitätsklinik Zürich, Réseau Fribourgeois de Santé Mentale, University of Greenwich, University of Ottawa, Ottawa Hospital, Ottawa Hospital Research Institute, Charité - Universitätsmedizin Berlin, Feinstein Institute for Medical Research, Donald & Barbara Zucker School of Medicine at Hofstra/Northwell, Zucker Hillside Hospital, FHNW University of Applied Sciences and Arts Northwestern Switzerland, University of California San Diego
Language: English
Topic: COVID-19 and Mental Health
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7129015468
