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Discovery of Marine Highly Congested Polycyclic Isodhilarane-Type Meroterpenoids as Potential Leads for Treating Liver Fibrosis by Activating the HSF1/AMPK Metabolic Axis

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c03055
Authors: Zhongping Jiang, Yue Chen, Shouyuan Wu, Junjie Wang, Feifei Liu, Jin Liu, Congjun Xu, Wanshan Li, Yong Rao, Ling Huang
Institutions: Hainan University, Lingnan Normal University, Hainan Normal University
Language: English

Topic: Liver physiology and pathology
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Hainan Province, Hainan University, Hainan Provincial Department of Science and Technology
Awards: G2837928654, G2916089361, G4128257149, 红树植物海漆中甘遂烷型三萜FXR激动剂的挖掘、结构优化及其抗NASH活性评价, G5122709173, G6187588207, G6310151098, G7355897279, G8762356863, G8986150441
OpenAlex ID: W7129030996
FWCI: 7.892
Cites: 41
Cited by: 2
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