Work

Reconsidering the scientific validity of the term “non-toxic” in toxicological risk assessment

Year: 2026

Type: article

Abstract: The term “non-toxic” is widely used in consumer product labeling despite the absence of a formal scientific or regulatory definition. Contemporary toxicology recognizes that adverse biological effects depend on dose, duration of exposure, route of entry, genetic variability, and underlying molecular mechanisms. This review critically examines the scientific limitations of the term “non-toxic,” with particular emphasis on chronic toxicity, genotoxic mechanisms, and carcinogenic processes. Evaluation of toxicological principles and regulatory practices indicates that the term is incompatible with current scientific understanding and may undermine accurate risk communication.

Source: Archives of Clinical Toxicology

DOI: 10.46439/toxicology.8.046

Authors: Gulzar R. Ahmad, Dildar Ahmad, Shan A. Rajput, Hassan Khan, Masood A. Shammas

Institutions: University of Houston, Harvard University, Dana-Farber Cancer Institute

Language: English

Topic: Carcinogens and Genotoxicity Assessment

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7129068200