Work

Study of the Benzylation Reactions of 6-aminopurine and Its Immobilization Properties in Hydrogel Capsules

Year: 2026

Type: article

Abstract: 6-Aminopurine is an important heterocyclic compound exhibiting pronounced biological activity and serving as a precursor of plant growth regulators and coordination ligands. In this study, the benzylation reactions of 6-aminopurine were investigated under various reaction conditions in order to obtain selectively substituted derivatives. The influence of solvent polarity, base strength, temperature, and reagent ratio on the direction of N-alkylation was analyzed, with particular attention to substitution at the N7 and N9 positions of the purine ring. The synthesized benzylated products were isolated and structurally characterized using FT-IR, UV–Vis and NMR spectroscopy, confirming successful modification of the heterocyclic system.

Source: Journal of Universal Science Research

DOI: 10.5281/zenodo.18657378

Authors: Ozoda Kamolova, Gayrat Haydarov, Foziljon Saitkulov, 3Qosim Zakhidov

Institutions: Tashkent State Agrarian University, Samarkand State University named after Sharof Rashidov

Language: English

Topic: Synthesis and Characterization of Heterocyclic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W7129079171

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