Comparative analysis of four sequencing platforms for methylation sequencing
Year: 2026
Type: article
Abstract: This study conducts a comprehensive assessment of four sequencing platforms: GenoLab M (Genemind), NovaSeq X (Illumina), T7 (MGI) and Salus Pro (Salus), focusing on different performance metrics related to methylation data. By analyzing data from plasma cfDNA samples, we assessed key metrics including sequencing quality, CpG coverage, data efficiency, and methylation level consistency. These findings aim to provide valuable insights into the consistency of sequencing platforms for researchers and laboratories when integrating multiple methylation datasets for analysis.
Source: BMC Research Notes
Authors: Jinxia Guan, Chuanchun Yang, Hongjun Gao, Shuanping Liu, Min Zheng, Yongjun Li, Baochen Du, Changling Zhang, Yuanyuan Guo, Qi Wang, Luyang Zhao, XiaoLiang Han
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,690
OpenAlex ID: W7129087579