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(E)-Methyl 3-(2-amino-4-chloro-6-morpholinopyrimidin-5-yl)acrylate

Year: 2026

Type: article

Abstract: The synthesis of methyl (E)-3-(2-amino-4-chloro-6-morpholinopyrimidin-5-yl)acrylate 3 was accomplished using a Schlosser-modified Wittig reaction. Complete 1H and 13C NMR signal assignments confirm the formation of E-alkene.

Source: Molbank

DOI: 10.3390/m2141

Authors: Jorge Trilleras, Efraín Polo-Cuadrado, Jairo Quiroga

Institutions: University of Atlántico, University of Concepción, Universidad del Valle

Language: English

Topic: Phosphorus compounds and reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $603

Funders: Universidad del Atlántico, Universidad de Concepción, Universidad del Valle

OpenAlex ID: W7129091394

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