Work

The “good” future is a mirage? – hyperdiploidy in childhood acute lymphoblastic leukemia

Year: 2026

Type: article

Abstract: • Review of cytogenetics in hyper diploid ALL of cytogenetics on Day 28 is feasible and can be implemented in all centres with cytogenetics data. • Duplicated hyper haploids chromosome 1q duplication, chromosome 6q deletion, isochromosome 17q, isochromosome 7q, and TP53 mutation may be associated with non-classical hyperdiploidy. • There is no added cost of this test for risk stratification which adds to the economic burden in resource-limited settings but a simple review of the cytogenetics data.

Source: Pediatric Hematology Oncology Journal

DOI: 10.1016/j.phoj.2026.100805

Authors: Vijayshree Muthukumar, Indhumathi Nagarathinam, Kavitha Ganesan, Ramya Uppuluri, Revathi Raj

Institution: Apollo Hospitals

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600