Year: 2026
Type: article
Abstract: An efficient variant of the venerable Fischer indole synthesis featuring the direct use of carboxylic acids as aldehyde surrogates was developed. The utility of this protocol was demonstrated by the one‐pot synthesis of a series of 3‐substituted indoles and 3,5‐, 3,6‐, 3,7‐disubstituted derivatives. This work would inspire chemists to develop other non‐decarboxylative transformations of carboxylic acids. More details are discussed in the article by Huang et al . on pages 795—803. image
Source: Chinese Journal of Chemistry
DOI: 10.1002/cjoc.70520
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W7129097825
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