Work

Microbiome-mediated colonization resistance to and countermeasures of Klebsiella pneumoniae

Year: 2026

Type: article

Abstract: Klebsiella pneumoniae intestinal colonization contributes to infectious and non-infectious diseases. Recent studies have uncovered the complex interplay between the gut microbiota and K. pneumoniae colonization, highlighting its role in disease development and progression and illustrating the potential of microbiome-based therapies. Yang et al. summarize that Klebsiella pneumoniae affects infectious and non-infectious disease via gut colonization; commensals provide colonization resistance, but K. pneumoniae adapts via multiple mechanisms.

Source: Nature Communications

DOI: 10.1038/s41467-026-69690-9

Authors: Yongqiang Yang, Willem van Schaik, Alan McNally, Zhiyong Zong

Institutions: Sichuan University, West China Hospital of Sichuan University, University of Birmingham

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $6,990