Work

A urologic manifestation of carney complex: Bilateral Sertoli tumors and scrotal myxoma in an adolescent male

Year: 2026

Type: article

Abstract: Carney complex (CNC) is a rare tumor syndrome caused by mutations in the PRKAR1A gene, characterized by endocrine tumors, cardiac and cutaneous myxomas, pigmented lesions, and testicular tumors. One to two thirds of affected males develop large cell calcifying Sertoli cell tumors (LCCSCTs), with rare involvement of scrotal soft tissues. We present a case of CNC in an adolescent male with bilateral LCCSCTs and a very large scrotal myxoma, resulting in azoospermia and pain requiring surgical management. This report highlights the urologic manifestations of CNC and outlines appropriate evaluation, treatment, and surveillance strategies relevant to pediatric and adolescent urologic practice.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2026.103383

Authors: Evan Walter, Avery Wolfe, Zhongxin Yu, Adam Rensing

Institutions: University of Minnesota, Children's Hospital of Oklahoma, University of Oklahoma

Language: English

Topic: Testicular diseases and treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160