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Regenerative Endodontics in Immature Permanent Teeth: A Comprehensive Review for Pediatric Rehabilitation

Year: 2026

Type: article

Abstract: Regenerative endodontic procedures (REPs) represent a transformative approach in managing necrotic immature permanent teeth, particularly in pediatric patients. Unlike traditional apexification techniques, REPs focus on biologically based regeneration using stem cells, bioactive scaffolds, and growth factors to restore the pulp–dentin complex. This review explores the evolution, biological foundation, current techniques, scaffold innovations, clinical outcomes, and limitations of REPs, with a focus on their relevance in pediatric dental rehabilitation. Emphasis is placed on the functional and psychosocial benefits of preserving natural tooth structure in children and adolescents.

Source: International Journal of Pedodontic Rehabilitation

DOI: 10.56501/intjpedorehab.102.ijped0007

Authors: Paridhi Tiwari, Darpan Nenava, Muskan Saini

Language: English

Topic: Endodontics and Root Canal Treatments

Subfield: Oral Surgery

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7129370577

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