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Abstract PS3-12-22: Tumor cell AADAT suppresses CD8+T cell function by depleting malate, driving progression in Triple-Negative Breast Cancer

Year: 2026

Type: conference-abstract

Source: Clinical Cancer Research

DOI: 10.1158/1557-3265.sabcs25-ps3-12-22

Authors: M. Chatterjee, F. Gu, L. Yu, D. Varghese, J. Park, B. Piyarathna, S. Thota, W. Zhang, Y. Gao, U. Rasaily, Y. Qiu, V. Putluri, B. Karanam, N. Chandandeep, B. Simons, J. Asirvatham, A. Rao, C. Morrison, G. Das, C. Ambrosone, E. Seeley, B. Kaipparettu, I. Kurland, N. Putluri, Q. Zhu, X. Zhang, A. Sreekumar

Institutions: Baylor College of Medicine, Albert Einstein College of Medicine, Dan L Duncan Comprehensive Cancer Center, Tuskegee University, Baylor Scott & White Medical Center - Temple, Baylor Scott & White Health, Roswell Park Comprehensive Cancer Center

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7129375154

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