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Post-laser in situ keratomileusis (LASIK) epithelial ingrowth after interface fluid syndrome

Year: 2026

Type: article

Abstract: Objectives: We present a case of epithelial ingrowth after late onset interface fluid syndrome, a rare complication after laser in situ keratomileusis (LASIK). Methods: This patient presented herself to the emergency department with corneal oedema due to endothelial failure after multiple intraocular surgeries. Anterior segment optical coherence tomography (OCT) showed a fluid filled pocket in the LASIK interface, 20 years after LASIK surgery. Results: As a result, she was diagnosed with late onset interface fluid syndrome which resolved after endothelial transplantation (DMEK). However, 3 months after surgery, epithelial ingrowth in the LASIK interface was noticed. We adopted a conservative approach as there was no progression after 3 weeks. Conclusions: Epithelial ingrowth is a rare complication after DMEK, which might be caused by interface fluid induced flap lifting and further facilitated by intraoperative flap manipulation during graft unfolding.

Source: PubMed

DOI: 10.3205/oc000267

Authors: Matthys, Emiel, Saelens, Isabelle, Delbeke, Heleen

Institution: Universitair Ziekenhuis Leuven

Language: English

Topic: Corneal surgery and disorders

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7129407377

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