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Evaluation of the clinical performance of a risk scoring model for venous thromboembolism prophylaxis in cesarean section for a largely Chinese population

Year: 2026
Type: article
Abstract: Background: Recommendations for venous thromboembolism (VTE) prophylaxis after cesarean section (CS) from authoritative guidelines differed significantly and may not be applicable to Chinese population. Objectives: This study aimed to evaluate the performance and safety of an adapted risk score prophylaxis protocol in a largely Chinese cohort. Methods: The risk assessment and preventive care for VTE for CS protocol was implemented from May 2017 for all patients undergoing CS. Those with moderate risk (VTE score, 2) would be prescribed mechanical prophylaxis using pneumatic cuff, and those with high risk (VTE score, ≥3) would be prescribed pharmacologic prophylaxis with low-molecular-weight heparin in addition to the pneumatic cuff. In this retrospective cohort study, the outcome of patients with CS from the time of implementation of the protocol to December 2024 (7.5 years) was compared with that of a preprotocol group with no prophylactic measures from January 2014 to April 2017. Results: = .043), while there was no increase in bleeding complications (0.96% in the preprotocol period vs 0.76% in the protocol period). Conclusion: Implementation of a standardized thromboprophylaxis protocol adapted for cesarean deliveries in our local obstetric population maintained pharmacologic thromboprophylaxis at a low rate and did not result in an increase in bleeding complications. A lower incidence of VTE was observed after implementation of the protocol than that in the preprotocol period.
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,250
OpenAlex ID: W7129503137
FWCI:
Cites: 29
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