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Beyond Thiol-Enzyme Inhibition: Sterically Bulky NHC-Au(I) Complexes are Catalytically Active Anticancer Agents with Reprogrammed Immunomodulatory Function

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Year: 2026
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/jacs.5c19777
Authors: Zhi Zhong, Haitao Liu, Qiong Wu, Bei Cao, Yujiao Peng, Moyi Liu, Liang-Mei Yang, Yue Lin, Ke-Bin Huang, Xiaolin Xiong, Jinsai Shang, Taotao Zou
Institutions: Sun Yat-sen University, State Key Laboratory of Respiratory Disease, Guangzhou Laboratory, Guangzhou Medical University, The Hong Kong University of Science and Technology (Guangzhou), Guangxi Normal University, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases
Language: English

Topic: Metal complexes synthesis and properties
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Guangzhou Science and Technology Program key projects, Science and Technology Planning Project of Guangdong Province, Basic and Applied Basic Research Foundation of Guangdong Province
Awards: G1539976974, G2896872638, G5475551143, G5600004614, G6183902507, G6624290900, G699191588, G8520809910, G858996846, G8698076023
OpenAlex ID: W7129594826
FWCI: 11.11
Cites: 131
Cited by: 4
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