A Case Report of Syphilitic Hepatitis
Year: 2026
Type: article
Study design: Case Report
Abstract: A 49-year-old woman presented to the emergency department with acute right upper quadrant pain. Laboratory results were consistent with cholestatic liver injury. Potential common causes—such as obstructive, viral, and autoimmune conditions—were excluded. She began developing systemic symptoms, including rash, vision changes, and headaches. The patient was subsequently found to have secondary syphilis with neurosyphilis and syphilitic hepatitis. Although syphilitic hepatitis is a rare presentation of the disease, syphilis should be considered as a possible cause of transaminitis with a cholestatic pattern of liver injury.
Institution: Mayo Clinic
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7129645009