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Rational Design of Imidazo[1,2- a ]pyridine as an Effective TLR7 Antagonist for the Treatment of Psoriasis: Research Combined with In Silico Study

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c02121
Authors: Peng Yao, Xing Li, Guisen Li, Mingge Song, Tianming Yu, Zuguo Zheng, Yue Zhao, Jiaxing Li, Dawei Wang, Yasheng Zhu, Yi Hou, Jiayu Ding, Hao Shen, Guoyu Zhang, Meijie Ji, Hua Yang, Ping Li, Zhihong Liu, Peng Yang
Institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine, Sun Yat-sen University, Nanjing General Hospital of Nanjing Military Command, Nanjing University
Language: English

Topic: Psoriasis: Treatment and Pathogenesis
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Jiangsu Province, State Key Laboratory of Natural Medicines, National Key Research and Development Program of China, Double First Class University Plan
Awards: G1397765892, G2047868811, G6875912043, G7681569759, G7821261902, G8191503321, G8233470851
OpenAlex ID: W7130317055
FWCI: 2.279
Cites: 90
Cited by: 1
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