Bridging Metabolomics and Nociception: The Arachidonic Acid–NMDA Receptor Axis in Burning Mouth Syndrome
Year: 2026
Type: article
Abstract: The Arachidonic Acid (AA)-NMDA Receptor Axis describes a crucial neurochemical pathway where glutamate activation of NMDA receptors releases AA. AA binds directly to NMDA receptor subunits, increasing their open probability and also affecting other receptors and cellular processes, linking neuronal activity to lipid signalling.
Source: Journal of Oral Rehabilitation
DOI: 10.1111/joor.70171
Author: Takahiko Nagamine
Institution: Institute of Science Tokyo
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7130322225