Work

Cardiometabolic and metabolic profiles in irritable bowel syndrome associated with type 2 diabetes

Year: 2026

Type: article

Study design: Observational Study

Abstract: We identified a distinct cardiometabolic risk profile in patients with IBS, characterized by elevated BMI, triglycerides, HbA1c, and reduced HDL-C levels. Metabolic phenotyping reveals a pattern in patients with IBS comparable with T2D profiles, including altered amino acid, glucose, and lipid metabolism.

Source: American Journal of Physiology-Endocrinology and Metabolism

DOI: 10.1152/ajpendo.00489.2025

Authors: Franziska Schmelter, Lotta Nowak, Paul Beier, Vivian Valeska Tetzlaff-Lelleck, Anna Kordowski, Bandik Föh, Oliver Witt, Torsten Schröder, Ulrich L. Günther, Yves Laumonnier, Benjamin A. H. Jensen, Stephan C. Bischoff, Stefanie Derer, Christian Sina

Institutions: University of Lübeck, University of Copenhagen, University of Hohenheim

Language: English

Topic: Gastrointestinal motility and disorders

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Bundesministerium für Bildung und Forschung

Award: Verbund INDICATE-FH - Neue Wege in der Diagnostik und Therapie von Nahrungsmittelunverträglichkeiten - Technologische Neuerungen zur Verbesserung der Diagnostik und Therapie von Weizenunverträglichkeit

OpenAlex ID: W7130389162

FWCI: 10.49

Cites: 39

Cited by: 2

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