Work

[18F]FDG-avid nodal gliomatosis associated with ovarian immature teratoma – The importance of histological confirmation

Year: 2026

Type: article

Abstract: Gliomatosis is a rare condition mainly associated with ovarian teratomas. It is characterized by the presence of mature glial tissue in extraovarian sites and most frequently found in the peritoneum (gliomatosis peritonei). Gliomatosis in the lymph nodes (nodal gliomatosis) has rarely been reported. We discuss a case of a 4-year-old girl with immature ovarian teratoma with concomitant gliomatosis peritonei and nodal gliomatosis, detected with magnetic resonance imaging (MRI) and Fluorine-18 fluorodeoxyglucose positron-emission tomography/computed tomography ([ 18 F]FDG PET/CT) as [ 18 F]FDG-avid lesions. Histologic examination showed mature well differentiated glial tissue. We aim to highlight the importance of histopathologic assessment of [ 18 F]FDG positive lesions that may initially appear metastatic.

Source: EJC Paediatric Oncology

DOI: 10.1016/j.ejcped.2026.100493