Multimodal Molecular Logic System: Designed on the Unimolecular Platform of an Intramolecular Charge Transfer‐Based Hydrazone Probe
Year: 2026
Type: article
Abstract: A novel unimolecular platform based on an intramolecular charge transfer‐active hydrazone probe was developed to construct versatile, opto‐chemically driven molecular logic devices. The probe exhibited dual‐channel responses: a ∼13.5‐fold fluorescence quenching at 442 nm with CN − and a 35 nm red‐shift with Hg 2+ . These discrete responses enabled the fabrication of XOR, INHIBIT, and XNOR logic gates at specific wavelengths (440, 355, and 395 nm, respectively), facilitating a molecular half‐subtractor and comparator. Time‐dependent optical transitions with Cu 2+ and Hg 2+ inputs produced dynamic gate switching (TRANSFER to OR, N‐TRANSFER to IMPLICATION). Furthermore, multianalyte combinations with F − , CN − , and Hg 2+ enabled the creation of a 3‐input, 3‐output Boolean circuit. Threshold‐guided absorbance (e.g., >0.15 for ON) ensured quantifiable logic states. The reversible nature of ion binding, demonstrated using EDTA, enhances reusability. This work advances tunable, multigate molecular computing for next‐generation bio‐optoelectronic interfaces.
Source: ChemPlusChem
Authors: Monaj Karar, Harshal V. Barkale, Nilanjan Dey
Institution: Birla Institute of Technology and Science, Pilani
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
Award: G1700595351
OpenAlex ID: W7130392308