Figure-of-8 Suture With a 3-Way Tap Versus Manual Compression After Atrial Fibrillation Ablation
Year: 2026
Type: article
Study design: Clinical Trial
Abstract: BACKGROUND: ) offers a simple and low-cost alternative to manual compression (MC). OBJECTIVES: The HARNESS (Haemostasis After Venous Access in Atrial Fibrillation Catheter Ablation) randomized controlled trial evaluated the efficacy of Fo8TAP and its impact on post-procedural bed rest duration. METHODS: with 2-hour bed rest (TAP-2). The primary endpoint of any access site complication before hospital discharge was assessed for superiority (TAP-4 vs MC-4) and noninferiority (TAP-2 vs TAP-4). Bleeding was graded from 1 (minor) to 4 (life-threatening). Secondary endpoints included times to hemostasis, catheter laboratory exit, and mobilization. RESULTS: (MC-4: 16 min; TAP-4: 9 min; TAP-2: 8 min; P < 0.001). Median time to mobilization was shortest with TAP-2 (MC-4: 242 min; TAP-4: 241 min; TAP-2: 122 min; P < 0.001). CONCLUSIONS: was superior to MC in lowering the incidence of access site complications and was associated with health care efficiencies. However, a 2-hour bed rest strategy failed to meet noninferiority criteria versus 4 hours. (Haemostasis After Venous Access in Atrial Fibrillation Catheter Ablation [HARNESS]; NCT06470555).
Source: JACC. Clinical electrophysiology
Authors: Mark T. Mills, Peter Calvert, Laurence Tidbury, Keith Wilson, Thomas Evans, Luca de Francesco, Ali Najm, Rajiv Tripathi, Jose Maria Farinha, Panagiotis Xydis, Kaung Thu, Richard Snowdon, Zoltan Borbas, Johan Waktare, Saagar N. Mahida, Nathan Denham, Reza Ashrafi, Derick Todd, Simon Modi, Vishal Luther, Dhiraj Gupta
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $5,000
OpenAlex ID: W7130504409