Efficacy of Intraoperative Adductor Canal Block Using Subhash Cocktail in Total Knee Arthroplasty: A Prospective Observational Study
Year: 2026
Type: article
Study design: Observational Study
Abstract: the efficacy and safety of intraoperative surgeon-administered ACB using the Subhash cocktail in patients undergoing TKA. Methods Study Design and SettingA prospective observational study was conducted at a tertiary care hospital over 8 months from January 2023 to October 2023.Ethical approval was obtained from the Institutional Ethics Committee approval no.: 156/SVMCH/IEC-Cert/May23.Written informed consent was obtained from all participants. IntroductIonTotal knee arthroplasty (TKA) is a commonly performed procedure for end-stage knee arthritis but is associated with significant postoperative pain that may delay rehabilitation.Traditional analgesic approaches, including epidural anesthesia, femoral nerve blocks, and periarticular infiltration, may impair quadriceps function or produce systemic side effects. 1 Adductor canal block (ACB) has emerged as an effective regional anesthesia technique that provides pain relief while preserving motor function.2 The Subhash cocktail, a combination of local anesthetics, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and adjuvants, has been proposed as an alternative to conventional periarticular infiltration.Its multimodal approach is conceptually supported by prior research on cocktail-based strategies for enhancing postoperative recovery.3 This study aimed to evaluate the efficacy and safety of intraoperative surgeon-administered ACB using the Subhash cocktail in patients undergoing TKA.Adductor canal block has emerged as an effective regional anesthesia technique that provides pain relief while preserving motor function.The Subhash cocktail, a combination of local anesthetics, opioids, NSAIDs, and adjuvants, has been proposed as an alternative to conventional periarticular infiltration.This study aimed to evaluate
Author: Karthik Velayudham
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7130505763