Work

Mechanism- and Physiology-Guided Drug-Coated Balloon-Only Percutaneous Coronary Intervention in Complex Multivessel Coronary Artery Disease: Insights From IVUS and vFFR

Year: 2026

Type: article

Abstract: We report the case of a 77-year-old man admitted with unstable angina. His medical history was notable for prior percutaneous coronary intervention (PCI) to the left anterior descending artery (LAD) in 2017, with implantation of 2 overlapping stents (2.5 × 15 mm and 2.75 × 18 mm), and diffuse large B-cell non-Hodgkin lymphoma treated within the previous 12 months. Coronary angiography revealed a significant in-stent restenosis (ISR) of the proximal LAD (Figure 1A, B), 40% stenosis of the left circumflex artery, and a long stenosis of the middle right coronary artery (RCA), visually estimated at 50% to 70% narrowed (Figure 2A, B).

Source: Journal of the Society for Cardiovascular Angiography & Interventions

DOI: 10.1016/j.jscai.2026.104391