Plant-derived nutritional components in thyroid disease-related neuropsychiatric disorders: mechanistic insights and advances
Year: 2026
Type: article
Abstract: Plant-derived nutritional components represent a promising adjunctive strategy for addressing neuropsychiatric manifestations of thyroid disorders. Although conventional hormone replacement normalizes biochemical parameters, many patients continue to experience neurocognitive impairment and affective symptoms, underscoring the complexity of thyroid-brain axis regulation. This review synthesizes recent advances on how plant-based nutritional approaches may modulate oxidative stress, neuroinflammation, neurotransmitter homeostasis, and blood-brain barrier integrity, and evaluates their emerging clinical applicability and existing evidence gaps. Overall, plant-based interventions may complement standard therapy and improve neuropsychiatric outcomes, though larger prospective studies are needed to clarify their efficacy and identify suitable patient subgroups.
Source: Frontiers in Nutrition
Institution: Nanjing University of Chinese Medicine
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7130508553