Work

Clinicoradiological Dissociation in a Giant Lytic Posterior Fossa Epidermoid Cyst: A Case Report

Year: 2026

Type: article

Abstract: Intracranial epidermoid cysts (ECs) are rare benign congenital lesions characterized by slow growth and late clinical presentation. Giant ECs of the posterior fossa are exceptionally uncommon and typically associated with early neurological deterioration due to the confined anatomy in this region. We report the case of a 74-year-old woman presenting with chronic headache and mild vertigo, with no focal motor or cranial nerve deficits. MRI revealed a giant extra-axial EC of the left posterior fossa with occipital bone lysis on CT scan. Despite the radiological findings, no acute hydrocephalus or intracranial hypertension was present. The patient underwent surgical resection. Histopathological examination confirmed the diagnosis of an EC. This case highlights the striking clinicoradiological dissociation that may be observed in giant posterior fossa ECs.

Source: Cureus

DOI: 10.7759/cureus.103911

Authors: Oumaima Monadi, Hajar Hamadi, Yassine Ait M’barek, Lamia Benantar, Khalid Aniba

Institution: Centre Hospitalier Universitaire Mohammed VI

Language: English

Topic: Teratomas and Epidermoid Cysts

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7130516044