Work

Automatic Identification of Fetal Acidosis Based on Three-Stage Training and Meta-Feature Fusion

Year: 2026

Type: article

Abstract: Fetal cardiotocography (CTG) is widely used to assess fetal health during labor and to screen for fetal acidosis. However, CTG interpretation relies heavily on clinicians’ experience and is affected by subjectivity and inconsistency, which limit diagnostic reliability. Most existing artificial intelligence approaches simplify fetal acid–base assessment into a binary classification, making it difficult to distinguish acidosis severity and restricting information for refined clinical decision-making. To address these limitations, this study formulates a three-class classification task—normal, moderate acidosis, and severe acidosis—based on the CTU-CHB dataset, using umbilical artery blood pH as the reference standard. A signal-first, conditionally enhanced, three-phase training and meta-feature fusion framework is proposed. In stage A, a CNN-BiLSTM-attention network performs end-to-end modeling of fetal heart rate signals, while a recall feedback-driven dynamic weighted loss alleviates class imbalance and identifies difficult samples. Stage B incorporates relevant clinical detection information for these difficult samples and applies multimodal feature fusion to enhance discrimination. Stage C constructs meta-features from the outputs of the first two stages to adaptively fuse classification preferences and uncertainty. Experimental results demonstrate that the proposed framework achieves an accuracy of 82.80 ± 2.82% and an F1 score of 78.84 ± 2.96%, effectively mitigating class imbalance and difficult sample classification, and providing reliable support for clinical decision-making in fetal acidosis.

Source: Applied Sciences

DOI: 10.3390/app16042045