Work

Identifying TMEM127-deficient pheochromocytomas/paragangliomas via RET overexpression by immunohistochemistry

Year: 2026

Type: preprint

Study design: Observational Study

Source: Research Square

DOI: 10.21203/rs.3.rs-8553860/v2

Authors: Cynthia Estrada-Zuniga, Rui Liang, Bethany Landry, Andrea Alvarez, Hector Gonzalez-Cantu, Viviane Nascimento da Conceicao, Rolando Trevino, David Gius, Sylvia Asa, James Powers, Tamara Prodanov, Anand Vaidya, Rodrigo Toledo, Jean Pierre Bayley, Debbie Cohen, Arthur Tischler, Karel Pacak, Faqian Li, Patricia Dahia

Institutions: The University of Texas at San Antonio Health Science Center, Case Western Reserve University, Tufts Medical Center, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Brigham and Women's Hospital, Vall d'Hebron Hospital Universitari, Leiden University, University of Pennsylvania

Language: English

Topic: Adrenal and Paraganglionic Tumors

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Cancer Prevention and Research Institute of Texas, University of Texas System, National Institutes of Health, University of Texas Health Science Center at San Antonio, National Cancer Institute

Awards: Dys-regulation of the MnSOD-Ac-ROS-HIF2a axis promotes IR / Cisplatin resistance phenotype, G61498961, G9000327191, Lineage Plasticity, due to Disruption of MnSOD Biology, drives resistance to Ionizing Radiation / Androgen Deprivation Therapy, Addressing biological and therapeutic gaps in rare neuroendocrine cancer with a novel organoid-based model

OpenAlex ID: W7130532790

Cites: 6

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