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Appendectomy for Chronic Abdominal Pain Caused by Appendiceal Neuroma

Year: 2026

Type: article

Abstract: This case reports a 35-year-old man with recurrent right lower quadrant (RLQ) pain initially suggestive of acute appendicitis who was diagnosed with functional abdominal pain syndrome after negative imaging and colonoscopy. Because of persistent pain, he underwent a diagnostic laparoscopy and appendectomy, where an appendiceal neuroma was diagnosed; this led to complete symptom resolution. This case highlights the importance of considering appendiceal neuroma in the differential for unexplained appendicitis-like RLQ pain, particularly when standard workups are inconclusive. The resolution of symptoms postsurgery suggests that exploratory surgery should be considered in patients with severe and persistent RLQ pain, even with negative imaging.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000001954

Authors: Jordana Herblum, Erin Kennedy, Andrea Covelli, Laura Targownik

Institutions: University of Toronto, Mount Sinai Hospital, University Health Network

Language: English

Topic: Appendicitis Diagnosis and Management

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7130658091

FWCI:

Cites: 8

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