Advances in Imaging-based Diagnosis and Treatment Strategies for AIDSRelated Cerebral Toxoplasmosis
Year: 2026
Type: article
Abstract: Cerebral toxoplasmosis is one of the most common opportunistic infections among AIDS patients. Clinical and neuroimaging manifestations are diverse and non-specific, resulting in frequent delayed diagnosis and even misdiagnosis, leading to neurological impairment, coma, and death. In addition to clinical and serological examinations, multimodal neuroimaging is indispensable for early diagnosis and subsequent treatment evaluation. Indeed, functional magnetic resonance imaging technologies and positron emission tomography provide complementary information for early diagnosis and treatment, which can improve prognosis when combined with prevention strategies. Recent advances in vaccine development have provided new hope for the prevention of cerebral toxoplasmosis. This article reviews multimodal imaging evaluation strategies and other recent clinical advances for the prevention, diagnosis, and treatment of AIDS-related cerebral toxoplasmosis.
Authors: Zhiguang Si, Hong Yang, Wangpin Meng, Ran Yang, Yunqing Wan
Institution: Kunming Medical University
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W7130661988