Work

Manometric ineffective esophageal motility does not progress over time: a single-center retrospective study

Year: 2026

Type: article

Abstract: Manometric ineffective esophageal motility (IEM) remains poorly understood. Patients who underwent ≥2 HRMs with ≥1 demonstrating IEM (CCv4.0) were included. Of 20 patients with IEM on initial HRM, 75% had IEM and 25% normal motility on subsequent HRM. Twelve patients had normal motility on initial HRM and IEM on subsequent HRM. No patients with IEM progressed to a major motility disorder. IEM appears to have a non-progressive manometric disease course.

Source: npj gut and liver.

DOI: 10.1038/s44355-026-00056-0