Work

Coexistence of MOG-IgG-associated bilateral optic neuritis with psoriasis vulgaris and psoriatic arthritis in an Asian patient: a rare case report

Year: 2026

Type: article

Abstract: BACKGROUND: Myelin oligodendrocyte glycoprotein-associated disease (MOGAD) is an inflammatory neurological disorder rarely associated with autoimmune disorders. We report the first case of MOGAD-associated optic neuritis in an Asian patient with psoriasis vulgaris and psoriatic arthritis. CASE PRESENTATION: A 53-year-old female with psoriasis vulgaris and psoriatic arthritis presented with bilateral optic neuritis. She was treated with intravenous methylprednisolone 1 g/day for three days, followed by a three-month oral prednisolone taper. The patient experienced near-complete visual recovery and remained relapse-free until present. CONCLUSIONS: Although rare, this case highlights the importance of recognizing MOGAD-associated optic neuritis in autoimmune patients, as prompt diagnosis and treatment can significantly improve outcomes.

Source: BMC Ophthalmology

DOI: 10.1186/s12886-026-04677-0

Authors: Chia-Wei Chang, Hsiu-Mei Huang, Nai-Wen Tsai, Shang-Hung Lin, Jong-Jer Lee, Yu-Ting Hsiao

Institutions: Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, Chang Gung Memorial Hospital

Language: English

Topic: Multiple Sclerosis Research Studies

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990