Work

Identification of quinolinyl-containing dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors with moderate potency towards acetylcholinesterase

Year: 2026

Type: article

Abstract: revealed key interactions with FAAH and sEH but limited interactions with AChE, suggesting directions for future structural modifications that could improve potency and selectivity.

Source: Results in Chemistry

DOI: 10.1016/j.rechem.2026.103159

Authors: Michael Gonzalez, Ryan West, Amanda Tsang, Olivia Ocampo, Paula K. Hudson, Stevan Pecic

Institution: California State University, Fullerton

Language: English

Topic: Cholinesterase and Neurodegenerative Diseases

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,870

Funders: National Science Foundation, National Institutes of Health, California State University, Fullerton, National Institute of General Medical Sciences

Awards: G2228269222, Cal State Fullerton MARC U*STAR Program, MRI: Acquisition of an ultra performance liquid chromatography mass spectrometer (UPLC-MS) for multi-disciplinary research

OpenAlex ID: W7130849934

FWCI: 3.862

Cites: 59

Cited by: 1

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