Deoxygenative Coupling Between Morita–Baylis–Hillman Acetates and Unprotected Cycloketone Oximes Enabled by Photoredox/Ti Dual Catalysis
Year: 2026
Type: article
Abstract: A photoredox/Ti dual‐catalyzed deoxygenative coupling reaction between Morita–Baylis–Hillman acetates and unprotected cycloketone oximes has been developed. A broad range of cyano‐containing trisubstituted alkenes have been expediently synthesized in good chemo‐ and stereo‐selectivities under very mild conditions. Mechanistic experiments, scale‐up reaction, and functionalization of complex molecules were conducted, in order to showcase the mechanistic features and robustness of this protocol.
Source: Advanced Synthesis & Catalysis
DOI: 10.1002/adsc.70317
Institution: Nanjing Agricultural University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W7130980309