Disseminated Mycobacterium haemophilum causing granulomatous mastitis
Year: 2026
Type: article
Study design: Case Report
Abstract: • Granulomatous mastitis caused by disseminated Mycobacterium haemophilum . We present the case of a 58-year-old female with celiac disease, obesity and recently diagnosed type 2 diabetes mellitus who developed a rash on her left thigh which spread and progressed to her arms, face, and abdomen. A biopsy of the left forearm grew Mycobacterium haemophilum . Weeks after the diagnosis of the M. haemophilum skin infection, the patient underwent a screening mammogram which showed new masses in both breasts. A biopsy of a left breast mass revealed cystic granulomatous inflammation with scattered neutrophils and lymphocytes within fibroadipose tissue. PCR and sequencing from breast tissue and AFB culture confirmed M. haemophilum . The patient was also later diagnosed with sinonasal involvement. No underlying immunodeficiency has been identified. This case highlights dissemination of M. haemophilum to multiple sites including skin, breast, and sinonasal tissues in a diabetic patient who was not otherwise immunocompromised. To our knowledge, it is the first reported case of granulomatous mastitis caused by M. haemophilum
Institution: Cleveland Clinic
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,470
OpenAlex ID: W7131297263