Work

Development of an inducible stable producer cell line for rAAV production

Year: 2026

Type: article

Source: Biochemical Engineering Journal

DOI: 10.1016/j.bej.2026.110144

Authors: Qiang Fu, Yongdan Wang, Emily Doleh, Mark Blenner, Seongkyu Yoon

Institutions: University of Massachusetts Lowell, University of Delaware

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Advanced Mammalian Biomanufacturing Innovation Center, National Science Foundation, Massachusetts Life Sciences Center, Korea Advanced Institute of Science and Technology, National Institutes of Health

Awards: IUCRC Phase II+: University of Massachusetts Lowell: Advanced Mammalian Biomanufacturing Innovation Center (AMBIC), Establishing a stable production cell line for recombinant AAV through synthetic dynamic regulation and reducing regulatory and metabolic limitations

OpenAlex ID: W7131619636

FWCI: 12.91

Cites: 31

Cited by: 4

Related to: 10