Heart rate variability in patients with newly diagnosed type 2 diabetes mellitus
Year: 2013
Type: article
Study design: Observational Study
Abstract: Diabetes mellitus can cause cardiovascular autonomic neuropathy and is associated with increased cardiovascular mortality. Materials and methods: We investigated cardiovascular autonomic neuropathy in diabetics and healthy controls by analysis of heart rate variability. Twenty-five diabetics and 22 controls, age- and sex-matched were included. The 24- hours Holter was used and the time domain parameters were measured. In the time domain we measured: the mean R - R interval (NN), the standard deviation of the R - R interval index (SDNN), the standard deviation of the 5-min R - R interval mean (SDANN), the root mean square of successive R - R interval differences (RMSSD) and the percentage of beats with a consecutive R - R interval difference > 50 ms (pNN50). Results: Diabetes patients had lower values for time-domain parameters than controls. Conclusion: Most heart rate variability parameters were lower in diabetic patients than in controls. These patients have to be intensively followed to prevent progression of cardiovascular autonomic dysfunction.
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7132672014