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A Novel Venous Leg Ulcer Fluid Analysis Method for Rapid Metabolic Profiling

Year: 2026

Type: article

Abstract: Venous leg ulcers (VLUs) are a major cause of morbidity with up to 30% failing to heal at 6 months. The biochemical composition of VLU exudates has been shown to be reflective of the wound microenvironment and correlates with wound healing status. Conventional metabolomic analyses of VLU fluid require lengthy sample collection, preprocessing, and laboratory workflows, limiting clinical utility. To overcome these limitations, a novel method for VLU fluid collection and analysis was developed and investigated.

Source: Journal of Vascular Surgery Venous and Lymphatic Disorders

DOI: 10.1016/j.jvsv.2025.102381

Authors: Matthew Tan, Kanin Pruekprasert, Alun Davies, Sarah Onida

Language: English

Topic: Wound Healing and Treatments

Subfield: Rehabilitation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,400

OpenAlex ID: W7132833258

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