Work

Liquid crystal-based interferometric detection of optical activity for glucose sensing

Year: 2026

Type: conference-paper

Abstract: We present an interferometric polarimetric system that uses a voltage-tunable liquid crystal cell to quantify glucose-induced optical activity. This approach eliminates mechanically moving parts and enables phase modulation through electrically controlled birefringence. Measurements were conducted in aqueous glucose solutions across the physiological concentration range, demonstrating stable and reproducible detection of polarization rotation. The setup addresses key limitations of conventional polarimetry, offering a compact and low-power platform for continuous, calibration-free metabolic monitoring. This work contributes to the development of next-generation optical sensors for wearable and implantable applications.

Source: Polarized Light and Optical Angular Momentum for Biomedical Diagnostics

DOI: 10.1117/12.3079140

Authors: Mahsa Nasehi, Ehsan Hassanpour, Mathias Bonmarin, Lilian Witthauer

Institutions: University of Bern, ZHAW Zurich University of Applied Sciences

Language: English

Topic: Optical Polarization and Ellipsometry

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W7133565665

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