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Abstract B014: A mechanistically distinct pan-RAS inhibitor, ADT-007, with robust antitumor activity evades resistance common to mutant-specific and pan-RAS Inhibitors

Year: 2026

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.rasoncother26-b014

Authors: Junwei Wang, Xi Chen, Sindhu Ramesh, Jeremy B. Foote, Chung-Hui Huang, Kristy L. Berry, Khalda Fadlalla, Bandi D. S. Reddy, Ganji P. Nagaraju, Elmar Nurmemmedov, Ivan Babic, Donald J. Buchsbaum, Asfar S. Azmi, Yulia Y. Maxuitenko, Adam B. Keeton, Bassel F. El-Rayes, Gary A. Piazza

Institutions: Auburn University, University of Alabama at Birmingham, Wayne State University, The Barbara Ann Karmanos Cancer Institute

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7133649137

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