Year: 2026
Type: preprint
Abstract: We identify an endoderm-restricted organelle in published volume electron microscopy datasets of C. elegans embryos. The organelle consists of a tubular ring surrounding a membrane-bound compartment harboring a prominent dense particle and exhibits a basal polarity and size concordant with canonical gut granules. This finding offers ultrastructural detail to recent evidence that gut granules are bi-lobed organelles with two distinct compartments.
Authors: Grant Archer, Sam Bartlowe, Bilegtugs Bayarbadrakh, Dawson Bok, Carolina Bushong, Anna Carroll, Megan Cole, Eric J. Dahl, Nicholas Denier, Ahmed Elewa, Hafsa El Harchi, Daniel Fisher, Hannah Grant, Rachel Grinfeld, Aliyah Grijalva, Aiden Hale, Cara Hendricks, Melek Iskandar, Sharron Kagan, Nidhi Mistry, Hope Keuneke, Lauryn Lammers, Annie Lyons, Quinn Maclin, Tatum Moore, Connor Munro, Gavin Nickerson, Brando Papalia, Kate Peacock, Lauren Ritzman, Aiden Ross, Rishi Samineni, Max Scales, Lillian Schotz, Wyatt Sikkema, Trinity Slabaugh, Autumn Sorenson, Raymond Swisher, Seyana Sutherland, Daniel Valdes, Faith Ward, Paulina Wojdyla
Institution: Miami University
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: green
Funder: University of Miami
Award: G4249210288
OpenAlex ID: W7155707941