Work

Abstract B002: Structural and functional analysis of the resistance mechanisms of KRAS-G12C secondary mutations to switch-II pocket inhibitors

Year: 2026

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.rasoncother26-b002

Authors: Matthew J. Whitley, Marcin Dyba, Mayukh Chakrabarti, Brian Smith, John-Paul Denson, Simon Messing, Ken Lin, Albert Chan, Trent E. Balius, Dwight V. Nissley, Frank McCormick, Anna E. Maciag, Dhirendra K. Simanshu

Institutions: Frederick National Laboratory for Cancer Research, BridgeBio Oncology Therapeutics (United States), University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7133755391

Cites:

Cited by:

Related to: