Year: 2026
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide Dynamic nuclear polarization (DNP) enhances the intensity of NMR signals by transferring polarization from electron spins to nuclei via microwave irradiation. Pulsed DNP methods offer more control on the spin dynamics than conventional continuous-wave approaches. Here, we report on-resonance and off-resonance DNP sequences optimized using effective Hamiltonians derived from continuous Floquet theory. Experiments at 80 K and 0.35 T using a sample of 5 mM Trityl OX063 in a glycerol-d 8 /D 2 O/H 2 O matrix (60:30:10, v/v/v) demonstrate that the optimized on-resonance sequence achieves 100 MHz electron offset bandwidth, while the off-resonance sequence centered at an electron offset of 50 MHz can cover 20 MHz, with 25 and 20 MHz of microwave power, respectively. These results demonstrate that continuous Floquet theory is a useful framework for the optimization of pulsed DNP sequences.
Institutions: ETH Zurich, Institute of Molecular Physical Science
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,500
OpenAlex ID: W7134225489