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Determinants of improved CGRP peptide binding kinetics revealed by enhanced molecular simulations

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Year: 2026
Type: article
Source: Biophysical Journal
DOI: 10.1016/j.bpj.2026.03.008
Authors: Ceren Kilinc, Katie M. Babin, Augen A. Pioszak, Alex Dickson
Institutions: Michigan State University, University of Oklahoma Health Sciences Center
Language: English

Topic: Protein Structure and Dynamics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: College of Arts and Sciences, Oklahoma State University, National Institutes of Health, College of Arts and Sciences, University of Oklahoma, National Institute of General Medical Sciences
Awards: RAMP-altered class B GPCR hormone binding and signaling, Oklahoma COBRE in Structural Biology, Revealing pathways and kinetics of molecular recognition with advanced molecular simulation algorithms, Oklahoma COBRE in Structural Biology
OpenAlex ID: W7134225994
FWCI: 2.955
Cites: 79
Cited by: 2
Related to: 10
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