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GeRnika: An R Package for the Simulation, Visualization and Comparison of Tumor Phylogenies

Year: 2026

Type: article

Abstract: The development of methods to study intratumoral heterogeneity and tumor phylogenies is a highly active area of research. However, the advancement of these approaches often necessitates access to substantial amounts of data, which can be challenging and expensive to acquire. Moreover, the assessment of results requires tools for visualizing and comparing tumor phylogenies. In this paper, we introduce GeRnika, an R package designed to address these needs by enabling the simulation, visualization, and comparison of tumor evolution data. In summary, GeRnika provides researchers with a user-friendly tool that facilitates the analysis of their approaches aimed at studying tumor composition and evolutionary history.

Source: The R Journal

DOI: 10.32614/rj-2025-042

Authors: Aitor Sánchez-Ferrera, Maitena Tellaetxe-Abete, Borja Calvo-Molinos

Institution: University of the Basque Country

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

OpenAlex ID: W7134945973

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