Work

Design, synthesis and biological assessment of erlotinib-1,2,3-triazole derivatives for anticancer applications

Year: 2026

Type: article

Abstract: antitumor activity while demonstrating minimal toxicity to normal tissues. These findings collectively suggest that 3d represents a promising candidate for further development as a potential therapeutic agent for hepatocellular carcinoma treatment.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d5md01149c

Authors: Qiyan Yao, Kexin Qu, Lan Wang, Mengmeng Huang, Longfei Mao, Sanqiang Li

Institution: Henan University of Science and Technology

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Natural Science Foundation of China-Henan Joint Fund