Work

Synthesis and Characterization of an N -Trifluoromethyl 1,4-Azaborine-Based Phosphine Ligand and Its Transition Metal Complexes

Year: 2026

Type: article

Abstract: The synthesis of N -trifluoromethyl 1,4-azaborine-based phosphine ligands (FinnPhos) is described. X-ray diffraction analysis of FinnPhos L1-CF3 and its N -methyl analogue reveals a stronger contribution of the neutral resonance form to the structure of the 1,4-azaborine ring. Density functional theory (DFT) calculations predict the FinnPhos to exhibit a unique η 3 -C,C,B coordination mode to Pd(0). We demonstrate that the N -trifluoromethyl ligand provides superior reactivity to its N -methyl and carbonaceous analogues in the Au-catalyzed cycloisomerization of 1,6-enynes.

Source: Inorganic Chemistry

DOI: 10.1021/acs.inorgchem.5c05782

Authors: Maxwell Eaton, Tomoya Ozaki, Bo Li, Shih-Yuan Liu

Institution: Boston College

Language: English

Topic: Organoboron and organosilicon chemistry

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: G2526851793, Bruker D8 VENTURE Diffractometer